Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

2.4K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
2.4K
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

15.0K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
15.0K
Cognitive Dissonance01:38

Cognitive Dissonance

37.5K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
37.5K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

279
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
279
Language and Cognition01:27

Language and Cognition

813
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
813
Cognitive Therapy01:25

Cognitive Therapy

1.3K
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving the neonatal mask ventilation skills of non-airway experts using the "Five Breath Method": A simulation study.

Pediatric discovery·2025
Same author

Why are critical event checklists not always used in the perioperative setting?: A retrospective survey.

PloS one·2025
Same author

Evaluation of the Pediatric Regional Anesthesia Time-Out Checklist: A Simulation Study.

Paediatric anaesthesia·2025
Same author

Does cognitive aid app design influence the speed of actions during a critical event?: A simulation study.

Paediatric anaesthesia·2024
Same author

Improving the Utility of Electroencephalogram-Guided Anesthesia for Prevention of Postoperative Delirium.

Anesthesia and analgesia·2021
Same author

Chest Compression Duration May Be Improved When Rescuers Breathe Supplemental Oxygen.

Aerospace medicine and human performance·2020

Related Experiment Video

Updated: Feb 13, 2026

Detection and Removal of Tooth-Colored Composite Resin Using the Fluorescence-Aided Identification Technique
05:42

Detection and Removal of Tooth-Colored Composite Resin Using the Fluorescence-Aided Identification Technique

Published on: July 27, 2022

4.4K

Pediatric trauma transfusion and cognitive aids.

Anna Clebone1

  • 1Department of Anesthesia and Critical Care, University of Chicago, Chicago IL 60637, USA.

Current Opinion in Anaesthesiology
|March 2, 2018
PubMed
Summary

Pediatric trauma patients may benefit from early tranexamic acid administration, particularly those with penetrating injuries. Further research is needed to optimize transfusion strategies and hemostatic management in critically ill children.

More Related Videos

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

20.5K
Routine Screening Method for Microparticles in Platelet Transfusions
09:49

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

16.6K

Related Experiment Videos

Last Updated: Feb 13, 2026

Detection and Removal of Tooth-Colored Composite Resin Using the Fluorescence-Aided Identification Technique
05:42

Detection and Removal of Tooth-Colored Composite Resin Using the Fluorescence-Aided Identification Technique

Published on: July 27, 2022

4.4K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

20.5K
Routine Screening Method for Microparticles in Platelet Transfusions
09:49

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

16.6K

Area of Science:

  • Pediatric Trauma Care
  • Hemorrhage Management
  • Coagulation Physiology

Background:

  • Trauma is a leading cause of death in children, with unique physiological differences impacting hemostasis.
  • Existing adult trauma research, including transfusion strategies, is not always directly applicable to pediatric populations.
  • Hemorrhage and trauma-induced coagulopathy are critical concerns in pediatric trauma patients.

Purpose of the Study:

  • To review recent advancements in pediatric trauma care.
  • To explore updated research on transfusion strategies and hemostatic management in children.
  • To highlight the need for pediatric-specific research in trauma resuscitation.

Main Methods:

  • Review of recent literature on pediatric trauma, focusing on physiology, coagulation, and resuscitation.
  • Analysis of studies investigating interventions like tranexamic acid and Factor VIIa.
  • Discussion of evolving concepts in anemia tolerance and massive transfusion protocols for children.

Main Results:

  • The PEDTRAX trial showed decreased mortality with early tranexamic acid in combat-related pediatric trauma (blast/penetrating injuries).
  • The applicability of these findings to blunt trauma, common in non-combat settings, remains uncertain.
  • Thromboelastography-guided recombinant Factor VIIa administration is an area for future research.

Conclusions:

  • Pediatric red blood cell physiology and coagulation profiles differ significantly from adults.
  • There have been significant shifts in understanding tolerable anemia levels and the application of damage control resuscitation in pediatric trauma.
  • Optimizing care requires continued pediatric-focused research on hypothermia avoidance and antifibrinolytic use.