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Design Consideration01:22

Design Consideration

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Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
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Tensile Strength Considerations of Concrete01:16

Tensile Strength Considerations of Concrete

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Considering the tensile strength of concrete involves recognizing that the theoretical strength of cement paste can be up to a thousand times higher than what is observed in practical applications. This significant discrepancy is largely attributed to the presence of microscopic cracks within the concrete. These cracks tend to amplify stress at their tips when a load is applied, a phenomenon explained by Griffith's theory of brittle fracture.
The dimensions and shape of a concrete specimen...
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Transmission Line Design Considerations01:23

Transmission Line Design Considerations

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Aluminum has become the material of choice for overhead transmission lines, surpassing copper due to its abundance and cost-effectiveness. The most prevalent type is the aluminum conductor, steel-reinforced (ACSR), which combines aluminum strands around a steel core. Other variants include all-aluminum conductors (AAC), all-aluminum alloy conductors (AAAC), aluminum conductor alloy-reinforced (ACAR), and aluminum-clad steel conductors. Advanced designs, such as aluminum conductors with steel...
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Gene Therapy00:59

Gene Therapy

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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Special considerations while measuring pulse01:13

Special considerations while measuring pulse

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Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
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Energy Considerations in Open Channel Flow01:27

Energy Considerations in Open Channel Flow

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Open channel flow, where a fluid flows with a free surface exposed to the atmosphere, is primarily governed by gravitational and surface effects, distinguishing it from closed conduit or pipe flow. In open channels such as rivers, canals, and artificial channels, energy analysis provides valuable insights into flow behavior and the relationship between depth, velocity, and slope.Specific Energy and Flow DepthIn open channel flow, the specific energy, E, combines the gravitational potential...
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[Some considerations about adherence to therapy.]

Maria Font1

  • 1UOC Servizio Farmaceutico Territoriale Azienda ULSS 9 Scaligera.

Recenti Progressi in Medicina
|March 2, 2018
PubMed
Summary

Poor adherence to therapy causes treatment failure across medicine, with complex interventions often ineffective. A holistic approach involving patient consent and deprescription is needed for chronic conditions.

Area of Science:

  • Pharmacology and Therapeutics
  • Patient Adherence Research

Background:

  • Poor adherence to medical therapy is a significant cause of treatment failure with wide-ranging health and economic consequences.
  • Existing interventions to improve adherence have yielded disappointing results, especially for chronic conditions, due to complexity and ineffectiveness.

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