Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Generation Time01:22

Generation Time

1.5K
Bacterial generation time, the period required for a bacterial population to double during its exponential growth phase, serves as a critical measure of microbial growth dynamics under optimal conditions. This parameter varies significantly across bacterial species and can be influenced by factors such as temperature, pH, and the availability of nutrients. For example, Escherichia coli can achieve a generation time of approximately 20 minutes, while Mycobacterium tuberculosis exhibits a much...
1.5K
Molecular Models02:00

Molecular Models

43.8K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
43.8K
Molecular Orbital Theory II03:51

Molecular Orbital Theory II

27.5K
Molecular Orbital Energy Diagrams
27.5K
Molecular Orbital Theory I02:35

Molecular Orbital Theory I

47.7K
Overview of Molecular Orbital Theory
47.7K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.0K
VSEPR Theory for Determination of Electron Pair Geometries
46.0K
Molecular and Ionic Solids02:54

Molecular and Ionic Solids

20.1K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
20.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Loss of Primary Cilia Potentiates <i>BRAF/MAPK</i> Pathway Activation in Rhabdoid Colorectal Carcinoma: A Series of 21 Cases Showing Ciliary Rootlet CoiledCoil (<i>CROCC</i>) Alterations.

Genes·2023
Same author

The Day-To-Day Practice of MMR and MSI Assessment in Colorectal Adenocarcinoma: What We Know and What We Still Need to Explore.

Digestive diseases (Basel, Switzerland)·2023
Same author

Mismatch repair deficiency as prognostic factor for stage III small bowel adenocarcinoma: A multicentric international study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2023
Same author

Lynch syndrome-related colorectal carcinomas are NTRK-negative.

Histopathology·2023
Same author

Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metastatic colorectal cancer treated with immune checkpoint inhibitors.

European journal of cancer (Oxford, England : 1990)·2023
Same author

IMMUNOREACT 5: female patients with rectal cancer have better immune editing mechanisms than male patients - a cohort study.

International journal of surgery (London, England)·2023

Related Experiment Video

Updated: Feb 5, 2026

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
05:33

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

1.1K

Molecular Diagnostics in Pathology: Time for a Next-Generation Pathologist?

Matteo Fassan1

  • 1From the Department of Medicine, Surgical Pathology and Cytopathology Unit, University of Padua, Padua, Italy.

Archives of Pathology & Laboratory Medicine
|March 2, 2018
PubMed
Summary

Pathologists integrate morphology, clinical data, and molecular profiling for precise cancer diagnosis and tailored therapy. Next-generation technologies revolutionize pathology, enabling multigene analysis even from small biopsies.

More Related Videos

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications
07:40

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

14.5K
On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System
14:15

On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System

Published on: February 23, 2018

17.5K

Related Experiment Videos

Last Updated: Feb 5, 2026

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
05:33

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

1.1K
Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications
07:40

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

Published on: June 29, 2020

14.5K
On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System
14:15

On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System

Published on: February 23, 2018

17.5K

Area of Science:

  • Oncology
  • Pathology
  • Molecular Diagnostics

Background:

  • Molecular targeted agents are widely used for solid tumors based on comprehensive cancer investigations.
  • The role of pathologists is evolving with new diagnostic technologies.

Purpose of the Study:

  • To update on the pathologist's role in therapeutic decisions.
  • To highlight the integration of next-generation technologies in pathology.

Main Methods:

  • Literature review of current topics.
  • PubMed database as the primary source.

Main Results:

  • Predictive biomarker evaluation relies on pathologic characterization and biospecimen processing.
  • Molecular testing requests increase as tumor material decreases (cytology/small biopsies).

Conclusions:

  • Next-generation technologies enable multigene, targeted profiling, revolutionizing traditional pathology.
  • Pathologists combine morphological, clinical, and molecular data for accurate diagnosis and tailored therapy.