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Corticocortical projections to area 1 in squirrel monkeys (Saimiri sciureus)
Christina M Cerkevich1, Jon H Kaas1
1Department of Psychology, Vanderbilt University, 301 David K. Wilson Hall, 111 21st Avenue South, Nashville, TN, 37203, USA.
The European Journal of Neuroscience
|March 2, 2018
Summary
Cortical area 1, crucial for tactile discrimination, receives inputs from various somatosensory and motor areas. This pattern of connections in squirrel monkeys is similar to that found in macaque monkeys, suggesting conserved primate brain organization.
Area of Science:
- Neuroscience
- Primate Somatosensory Cortex
Background:
- Cortical area 1 is a non-primary somatosensory region in the primate anterior parietal cortex.
- It plays a critical role in tactile discrimination.
Purpose of the Study:
- To determine the corticocortical projections to area 1 in squirrel monkeys.
- To compare these projections with those found in other primate species.
Main Methods:
- Multiple injections of anatomical tracers into defined body part representations in area 1.
- Multiunit microelectrode mapping to define body part representations.
Main Results:
- Area 1 exhibits strong intrinsic connections within body part representations.
- It receives somatotopically matched inputs from areas 3b, 3a, 2, and 5.
- Somatosensory areas (S2, PV, PR, VS) and motor areas (M1, PMd, PMv, SMA) project to area 1.
- Inputs also originate from medial wall cingulate motor and sensory areas.
Conclusions:
- The pattern of projections to area 1 in squirrel monkeys is similar to that observed in Old World macaque monkeys.
- This suggests a conserved organization of cortical inputs to area 1 across anthropoid primates.
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