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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
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Allergic Contact Dermatitis Due to Paraphenylenediamine: An Update
B Encabo Durán1, D Romero-Pérez1, J F Silvestre Salvador1
1Servicio de Dermatología, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, España.
Actas Dermo-Sifiliograficas
|March 3, 2018
Summary
Paraphenylenediamine (PPD) allergy is rising, especially in young individuals. This review covers PPD sources, interactions, and provides an algorithm for diagnosing and treating PPD allergic contact dermatitis.
Area of Science:
- Dermatology
- Toxicology
- Allergology
Background:
- Paraphenylenediamine (PPD) is a common chemical used in hair dyes and tattoos.
- Allergic contact dermatitis to PPD is a growing concern, particularly among younger populations.
Purpose of the Study:
- To review the primary sources and interactions of PPD.
- To present a diagnostic and treatment algorithm for suspected PPD allergy.
Main Methods:
- Literature review of PPD sources and interactions.
- Development of a clinical algorithm for PPD allergy management.
Main Results:
- Identified key sources of PPD exposure, including hair dyes and henna tattoos.
- Outlined potential cross-reacting substances.
- Proposed a structured approach to diagnosis and treatment.
Conclusions:
- Increasing PPD allergy necessitates awareness of exposure sources.
- A systematic approach aids in the diagnosis and management of PPD allergic contact dermatitis.
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