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Related Concept Videos

One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

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Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
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Two-Compartment Open Model: IV Infusion01:15

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A two-compartment model is a vital tool in pharmacokinetics, providing an essential understanding of drug behavior, especially for those administered via zero-order intravenous infusion. This model outlines two compartments: the central compartment, where elimination occurs, and the peripheral compartment.
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Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

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IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
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IV Infusion to Oral Dosing: Conversion Methods01:28

IV Infusion to Oral Dosing: Conversion Methods

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The development of extended-release formulations has facilitated the transition from intravenous to oral medication, offering a more convenient and patient-friendly approach to drug administration. This transition, however, requires careful management to ensure that therapeutic drug levels are maintained, preserving efficacy and avoiding adverse effects. Understanding pharmacokinetic principles and dosage calculations is critical during this process.Pharmacokinetics of the...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

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Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
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Related Experiment Video

Updated: Feb 13, 2026

Intravenous Injections in Neonatal Mice
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Intravenous lidocaine infusion.

G Soto1, M Naranjo González2, F Calero1

  • 1Médico Anestesiólogo, Hospital Escuela Eva Perón, Granadero Baigorria, Argentina.

Revista Espanola De Anestesiologia Y Reanimacion
|March 3, 2018
PubMed
Summary
This summary is machine-generated.

Systemic lidocaine infusion offers significant benefits, including pain relief and reduced opioid use. This review explores its pharmacology and clinical applications for enhanced recovery and potential future uses.

Keywords:
Anestesia libre de opioidesCancer recurrenceDisfunción cognitiva posoperatoriaHiperalgesia inducida por opioidesIntravenous lidocaineLidocaína intravenosaOpioid free anaesthesiaOpioid-induced hyperalgesiaPost-operative cognitive dysfunctionRecurrencia de cáncer

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Area of Science:

  • Anesthesiology and Pain Management
  • Pharmacology
  • Surgical Recovery

Background:

  • Peri-operative systemic lidocaine infusion possesses analgesic, anti-hyperalgesic, and anti-inflammatory effects.
  • It can decrease opioid and inhalational anesthetic requirements, promote early bowel function return, and shorten hospital stays.

Purpose of the Study:

  • To review the pharmacology and clinical indications of peri-operative lidocaine infusion.
  • To highlight emerging research areas and its role in enhanced recovery protocols.

Main Methods:

  • This is a narrative review.
  • It synthesizes findings from recent systematic reviews and meta-analyses on lidocaine infusion in various surgical settings.

Main Results:

  • Lidocaine infusion is effective in open, laparoscopic, and ambulatory surgeries.
  • It shows promise as an analgesic adjunct in enhanced recovery after surgery (ERAS) protocols.

Conclusions:

  • Peri-operative lidocaine infusion is a valuable tool for multimodal analgesia.
  • Further research is investigating its potential in chronic post-surgical pain, cognitive dysfunction, and cancer recurrence.