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Related Experiment Videos

Iododerma occurring after orally administered iopanoic acid.

O Boudoulas, R J Siegle, R E Grimwood

    Archives of Dermatology
    |March 1, 1987
    PubMed
    Summary

    A patient with multiple myeloma experienced a rare skin reaction, iododerma, after consuming iopanoic acid for an X-ray. This case highlights a potential adverse effect of oral contrast agents in myeloma patients.

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    Area of Science:

    • Dermatology
    • Radiology
    • Oncology

    Background:

    • Multiple myeloma is a cancer of plasma cells.
    • Oral cholecystography uses contrast agents to visualize the gallbladder.
    • Iododerma is a skin reaction to iodine.

    Observation:

    • A 45-year-old male patient with multiple myeloma underwent oral cholecystography.
    • The patient received iopanoic acid, an oral radiocontrast dye.
    • Skin lesions consistent with iododerma appeared two days post-exposure.

    Findings:

    • This is the first reported case of iododerma linked to multiple myeloma.
    • The reaction occurred after oral ingestion of iopanoic acid.
    • Multiple exposures within a week preceded the skin manifestation.

    Implications:

    • Clinicians should be aware of potential iododerma in multiple myeloma patients receiving oral contrast agents.
    • Further research may be needed to understand this specific drug-induced hypersensitivity.
    • This case underscores the importance of detailed patient history in diagnosing adverse drug reactions.

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