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Non-muscle myosins and the podocyte

Marina Noris1, Giuseppe Remuzzi2,3

  • 1Mario Negri Institute for Pharmacological Research, Clinical Research Center for Rare Diseases "Aldo e Cele Daccò", Department of Molecular Medicine, Ranica, Italy.

Clinical Kidney Journal
|March 3, 2018
PubMed
Summary

Podocyte foot process effacement causes proteinuria. Non-muscle myosins are crucial for the podocyte contractile apparatus, maintaining kidney filtration, as shown in hereditary proteinuric diseases.

Keywords:
actin cytoskeletonfocal segmental glomerulosclerosisnon-muscle myosinpodocyte foot processesproteinuria

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