Related Experiment Video
Updated: Feb 13, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
Published on: October 2, 2018
Haemodialysis in massive caffeine intoxication
Kathrin Fausch1, Dominik E Uehlinger1, Stephan Jakob2
1Department of Nephrology and Hypertension, University Hospital, University of Bern, Inselspital, Bern, Switzerland.
Abstract:
Caffeine is the most widely consumed psychoactive substance worldwide. Intoxication causes central nervous system and haemodynamic complications, which have significant mortality rates. We report the case of a 39-year-old woman who ingested ∼0.5 mol (100 g) of pure caffeine, leading to a peak serum concentration of 2.95 mmol/L (574 mg/L). Three consecutive haemodialysis sessions caused serum caffeine reduction rates of 66, 46 and 45%, indicating that the unbound caffeine fraction is not dose linear in this high serum caffeine concentration range. Aggressive and repeated haemodialysis sessions may be of benefit in cases of severe caffeine intoxication.
More Related Videos
Related Concept Videos
Biological Effects of Radiation
The Colonization of Land
Nuclear Fusion
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
Types of Radioactivity
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:

