Related Experiment Video
Updated: Feb 13, 2026
Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
Published on: October 9, 2014
Influence of Backscatter Radiation on Cranial Bone Fixation Devices
Yoshiaki Sakamoto1, Naoyoshi Koike2, Hideyuki Takei2
1Department of Plastic and Reconstructive Surgery.
Titanium and resorbable (polylactic acid-polyglycolic acid) cranial fixation devices influence radiation dose. Resorbable plates may reduce radiation ulcer risk compared to titanium during postoperative radiotherapy.
Area of Science:
- Medical Physics
- Biomaterials Science
- Radiation Oncology
Background:
- Postoperative radiotherapy can lead to skin ulceration over cranial implants.
- The impact of radiation backscatter from cranial fixation devices on ulcer formation is not well understood.
Purpose of the Study:
- To investigate radiation backscatter dose variations from different cranial bone fixation devices.
- To simulate the effects of postoperative radiotherapy in an experimental model.
Main Methods:
- Assessed radiation backscatter doses for resorbable (polylactic acid-polyglycolic acid) and titanium plates.
- Irradiated samples using 6 and 10 MV photon beams from a linear accelerator.
- Measured doses using an ionization chamber and radiochromic films.
Main Results:
- Backscatter radiation decreased with depth for water and polylactic acid-polyglycolic acid.
- Titanium plates showed increased backscatter radiation near the scalp surface.
- Higher radiation doses were observed at 10 MV compared to 6 MV for all materials.
- Fixation devices amplified radiation dose compared to water at 6 MV.
Conclusions:
- Resorbable (polylactic acid-polyglycolic acid) fixation devices may decrease the risk of radiation ulcers.
- Material selection for cranial fixation is crucial in patients undergoing radiotherapy.
More Related Videos
07:41An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016
13:16Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Related Concept Videos
01:27Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
01:14Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
02:59Biological Effects of Radiation
01:17Radiation: Applications
The average...
01:03Fixation and Sectioning
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
01:05Absorption of Radiation