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Updated: Feb 13, 2026

Isolation of Dendritic Cells from the Human Female Reproductive Tract for Phenotypical and Functional Studies
Published on: March 13, 2018
The cell surface phenotype of human dendritic cells
Georgina J Clark1, Pablo A Silveira1, P Mark Hogarth2
1Dendritic Cell Research, ANZAC Research Institute, Concord, NSW, Australia; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Abstract:
Dendritic cells (DC) are bone marrow derived leucocytes that are part of the mononuclear phagocytic system. These are surveillance cells found in all tissues and, as specialised antigen presenting cells, direct immune responses. Membrane molecules on the DC surface form a landscape that defines them as leucocytes and part of the mononuclear phagocytic system, interacts with their environment and directs interactions with other cells. This review describes the DC surface landscape, reflects on the different molecules confirmed to be on their surface and how they provide the basis for manipulation and translation of the potent functions of these cells into new diagnostics and immune therapies for the clinic.
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