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Efficacy and safety of electroacupuncture for post stroke depression: study protocol for a randomized controlled
Wa Cai1, Wen Ma1, Guan-Tao Wang1
1Department of Acupuncture, Shanghai Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Electroacupuncture (EA) shows promise for treating poststroke depression (PSD) with fewer side effects than antidepressants. This trial investigates EA
Area of Science:
- Neurology
- Integrative Medicine
- Clinical Trials
Background:
- Poststroke depression (PSD) is linked to increased mortality.
- Electroacupuncture (EA) offers a potentially safer and more effective alternative to antidepressants for PSD.
- This study aims to validate EA's efficacy and safety in PSD patients.
Purpose of the Study:
- To provide robust evidence for the effectiveness of electroacupuncture (EA) in treating poststroke depression (PSD).
- To assess the safety profile of EA treatment in patients experiencing PSD.
- To compare EA with sham EA in a randomized controlled trial setting.
Main Methods:
- A single-blind, single-center, randomized controlled trial involving 62 participants.
- Participants are randomized to receive either traditional EA or sham EA over 4 weeks (12 sessions).
- Primary outcome: Hamilton Rating Scale for Depression; Secondary outcomes: Zung SDS, NIHSS, BI, TCM Depression Scale.
Main Results:
- This section is to be filled once the trial results are available.
- The study is ongoing and results are pending.
- Data collection and analysis are in progress.
Conclusions:
- The trial is expected to demonstrate the efficacy and safety of EA for PSD.
- Positive findings would support EA as a preferred treatment option for poststroke depression.
- Results will contribute significant clinical evidence for EA in managing PSD.
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