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When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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Related Experiment Video

Updated: Feb 13, 2026

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation
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Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

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Precision medicine in hearing loss.

Jason R Rudman1, Christine Mei1, Sara E Bressler1

  • 1Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Journal of Genetics and Genomics = Yi Chuan Xue Bao
|March 4, 2018
PubMed
Summary

Precision medicine (PM) offers tailored healthcare using genetic and lifestyle data. This approach is revolutionizing hearing loss (HL) treatment by enabling predictive, personalized, and participatory care strategies.

Keywords:
GeneticsHearing lossPersonalized medicinePrecision medicine

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Area of Science:

  • Genetics and genomics
  • Audiology
  • Precision medicine

Background:

  • Hearing loss (HL) is a prevalent global sensorineural disorder, often with a monogenic cause.
  • Advancements in genetic sequencing and data analysis position HL for precision medicine (PM) integration.
  • PM focuses on customized medical care based on individual patient data.

Purpose of the Study:

  • To review current and future applications of PM in HL, focusing on its four core qualities (P4): predictive, personalized, patient-centered, and participatory.
  • To propose a strategy for integrating HL PM into research, electronic medical records, and clinical practice.
  • To discuss ethical and economic considerations of genomics-based HL treatment.

Main Methods:

  • Literature review of precision medicine applications in hearing loss.
  • Analysis of the four core qualities of PM (P4) in the context of HL.
  • Strategic framework development for HL PM implementation.

Main Results:

  • PM strategies can enhance HL diagnostics, prognostics, and individualized treatment.
  • Integration of PM into research and clinical practice is feasible and beneficial.
  • Ethical and economic factors require careful consideration for successful genomics-based HL care.

Conclusions:

  • Precision medicine offers a transformative approach to managing the diverse causes and presentations of hearing loss.
  • Integrating PM principles into translational research and clinical practice is key to individualized hearing healthcare.
  • Hearing specialists are well-positioned to lead the adoption of PM for improved patient outcomes.