Related Experiment Video
Updated: Feb 13, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
Short communication: Sex-linked differences in gamma-aminobutyric acid (GABA) are related to social functioning in
Melissa Kirkovski1, Chao Suo2, Peter Gregory Enticott1
1Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia; Monash Alfred Psychiatry Research Centre, The Alfred and Central Clinical School, Monash University, Clayton, Australia.
Abstract:
Magnetic resonance spectroscopy (MRS) was utilized to investigate sex differences in gamma-aminobutyric acid (GABA) between adults with autism spectrum disorder (ASD) and neurotypical (NT) controls. GABA at the right superior temporal sulcus (STS) is reported for 12 ASD and 14 NT participants. The results show no group differences in GABA. There was, however, a significant positive association between GABA at the STS and autism-related social impairments in females with ASD. These findings provide preliminary support for sex differences in GABAergic distribution and processes that contribute to social functioning in ASD.
Related Concept Videos
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Sex-linked Disorders
The Electromagnetic Spectrum
Social Anxiety Disorder
Social Foundations of Self IV: Self in Digital Communication
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein....

