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01:24Chronic Obstructive Pulmonary Disease
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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
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01:20Chronic Obstructive Pulmonary Disease-I: Introduction
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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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01:29Chronic Obstructive Pulmonary Disease-V: Management
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Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
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01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
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01:30Chronic Obstructive Pulmonary Disease-V: Nursing Management
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Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
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Assessment
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01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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[Pulmonary veno-occlusive disease].
A Boucly1, B Girerd1, D Bourlier1
1Faculté de médecine, university Paris-Sud, 94270 Le Kremlin-Bicêtre, France; Département hospitalo-universitaire (DHU) thorax innovation (TORINO), service de pneumologie, centre de référence de l'hypertension pulmonaire sévère, hôpital de Bicêtre, université Paris-Sud, AP-HP, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France; UMR_S999, Inserm, laboratoire d'excellence (LabEx) en recherche sur le médicament et l'innovation thérapeutique (LERMIT), hôpital Marie-Lannelongue, university Paris-Sud, 92350 Le Plessis-Robinson, France.
Revue Des Maladies Respiratoires
|March 5, 2018
Summary
Pulmonary veno-occlusive disease (PVOD) is a rare pulmonary hypertension form. Diagnosis relies on noninvasive methods, as lung biopsy is risky, and lung transplant is the main treatment.
Keywords:
DiagnosisDiagnosticMaladie veino-occlusive pulmonairePrognosisPronosticPulmonary veno-occlusive diseaseTherapyTraitementMore Related Videos
Area of Science:
- Cardiology
- Pulmonology
- Rare Diseases
Background:
- Pulmonary veno-occlusive disease (PVOD) is a rare pulmonary hypertension (PH) subtype.
- It involves pulmonary venule remodeling and angioproliferation.
- PVOD encompasses idiopathic, heritable, drug-induced, and connective tissue-associated forms.
Purpose of the Study:
- To summarize the key aspects of Pulmonary Veno-occlusive Disease (PVOD).
- To highlight diagnostic challenges and treatment limitations for PVOD.
Main Methods:
- Review of existing literature on PVOD.
- Noninvasive diagnostic approach including oxygen parameters, diffusing capacity for carbon monoxide, and high-resolution computed tomography (HRCT).
Main Results:
- PVOD shares clinical presentation with pulmonary arterial hypertension (PAH) but has a worse prognosis.
- Lung biopsy is contraindicated due to bleeding risk.
- Noninvasive methods support PVOD diagnosis.
- PAH-targeted therapies can induce pulmonary edema in PVOD patients.
Conclusions:
- PVOD requires a distinct diagnostic and therapeutic strategy compared to PAH.
- Lung transplantation is the primary definitive treatment for eligible PVOD patients.
- No evidence-based medical therapy currently exists for PVOD.