Related Experiment Video
Updated: Feb 13, 2026
Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
Published on: July 12, 2018
Aichivirus in Children with Diarrhea in Northern Italy
Massimiliano Bergallo1,2, Ilaria Galliano1,2, Paola Montanari1,2
1Department of Public Health and Pediatric Sciences, University of Turin Medical School, Turin, Italy.
Insights
Aichivirus (AiV) A was detected in pediatric patients in Piedmont, Italy, marking its first identification in the region. This finding suggests AiV may contribute to a small fraction of childhood diarrhea cases.
Area of Science:
- Virology
- Pediatric Gastroenterology
Background:
- Aichivirus (AiV) A is a known pathogen associated with diarrhea outbreaks in children and young adults.
- Previous studies indicate a prevalence of 0.9-4.1% for AiV A.
Purpose of the Study:
- To report the first detection of Aichivirus A in pediatric patients in Piedmont, Italy.
- To investigate the presence of AiV A in children with acute gastroenteritis.
Main Methods:
- 159 fecal specimens from infants and children with acute gastroenteritis were analyzed.
- Specimens were previously screened for common viral pathogens including rotaviruses, adenoviruses, noroviruses, human parechoviruses, saliviruses, and sapoviruses.
- Real-time polymerase chain reaction was used for AiV A detection.
Main Results:
- Aichivirus A was detected in 1 out of 159 (0.62%) pediatric cases.
- The detection of AiV A occurred as a monoinfection in January.
- Norovirus GII was the most prevalent virus (33.80%) in the study cohort.
Conclusions:
- This study reports the first identification of Aichivirus A in Piedmont, Italy.
- AiV A is associated with a limited number of diarrhea cases in pediatric patients.
Objective:
Since its discovery, Aichivirus (AiV) A has been detected, with an incidence of 0.9-4.1%, primarily when studying outbreaks of diarrhea in children or young adults. In this paper, we report the first detection of AiV in Piedmont, Italy, in pediatric patients.
Methods:
A total of 159 fecal specimens (from 96 males and 63 females) previously screened for rotaviruses, adenoviruses, noroviruses, human parechoviruses, saliviruses, and sapoviruses were collected from infants and children with acute gastroenteritis.
Results:
The most commonly detected virus was norovirus GII (33.80%), fol lowed by rotavirus (21.30%), astrovirus (18.87%), boca virus (13.92%), sapovirus (10.90%), parechovirus (8%), norovirus GI (6.70%), adenovirus (1%), and salivirus (0.52%). Real-time polymerase chain reaction detected AiV A in 1 (0.62%) case subjects. AiV A was detected in monoinfection only in January.
Conclusions:
Our results indicate that AiV may be associated with a limited number of diarrhea cases in pediatric patients.
Related Concept Videos
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:29Drug Dosing: Infants and Children
01:35Pedigree Analysis
01:10Nature and Nurture
01:49Probability Laws