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Streptomyces spp. in the biocatalysis toolbox.
Jelena Spasic1, Mina Mandic1, Lidija Djokic1
1Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, Belgrade, 11000, Serbia.
Applied Microbiology and Biotechnology
|March 5, 2018
Summary
Streptomyces bacteria are a rich source of bioactive molecules and biocatalytic enzymes for biotechnology. Advances in technology enhance enzyme discovery and engineering for sustainable bioeconomy applications.
Area of Science:
- Microbiology
- Biotechnology
- Biocatalysis
Background:
- Streptomyces are prolific sources of bioactive molecules and enzymes.
- Versatile metabolism enables their use in biotechnological applications like green chemistry and biopharmaceutical production.
- Technological advancements facilitate enzyme discovery and engineering.
Purpose of the Study:
- To review the role of Streptomyces in biocatalysis.
- To provide an overview of novel biocatalyst discovery and applications from Streptomyces.
- To highlight the potential of Streptomyces biocatalysts in industrial settings.
Main Methods:
- Literature search of PubMed and Web of Science databases (2000-2017).
- Analysis of research publications on Streptomyces and biocatalysis.
- Review of technological advances in enzyme discovery and engineering.
Main Results:
- Over 20,100 publications identified, indicating significant research interest.
- A steady increase in references (228 for 2000-2017) shows growing utilization of Streptomyces biocatalysts.
- Streptomyces enzymes are valuable for green chemical transformations, biopharmaceutical, and biofuel production.
Conclusions:
- Streptomyces are a key resource for biocatalysis.
- Technological progress is accelerating the discovery and application of Streptomyces-derived enzymes.
- These biocatalysts hold significant promise for sustainable bioeconomy and industrial applications.
