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A New Ex Vivo Model for the Evaluation of Endoscopic Submucosal Injection Material Performance
Published on: October 19, 2018
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Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
Keshav Kukreja1, Suma Chennubhotla1, Bharat Bhandari1
1Divisions of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, Houston, TX, USA.
Clinical Endoscopy
|March 6, 2018
Summary
Endoscopic suturing effectively closes large defects after endoscopic resection procedures like EMR, ESD, and EFTR. This minimally invasive technique demonstrates a high success rate and low complication risk for gastrointestinal defect closure.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Minimally Invasive Procedures
Background:
- Endoscopic resection techniques like EMR, ESD, and EFTR can create large defects.
- Primary closure of these defects is crucial for patient outcomes.
- Endoscopic suturing offers a minimally invasive approach to defect closure.
Purpose of the Study:
- To systematically review the literature on endoscopic suturing for primary closure of large defects.
- To evaluate the efficacy, outcomes, and complications of endoscopic suturing after EMR, ESD, and EFTR.
Main Methods:
- Systematic literature search of PubMed up to 2016.
- Inclusion of six original articles (four human, two non-human subjects).
- Analysis of procedural indications, details, success rates, outcomes, and complications.
Main Results:
- Mean success rate of 97.4% (100% in humans, 95.4% in non-humans).
- Procedural time varied from 7 to 89 minutes.
- No reported impact on mortality; low complication rates.
Conclusions:
- Endoscopic suturing is a safe and effective technique for primary closure of large defects.
- It is suitable for defects resulting from EMR, ESD, and EFTR.
- The technique offers high success and low complication rates in gastrointestinal endoscopic surgery.
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