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Area of Science:

  • Emergency Medicine
  • Pharmacology
  • Pulmonology

Background:

  • Tranexamic acid (TXA) is a well-established antifibrinolytic agent used for bleeding complications.
  • Previous research has explored oral, intravenous, and topical TXA administration.
  • Limited data exists on the efficacy and safety of nebulized TXA.

Observation:

  • A case of massive hemoptysis was successfully managed with nebulized TXA in the emergency department.
  • The administration of nebulized TXA led to the rapid cessation of bleeding.

Findings:

  • Nebulized TXA effectively controlled massive hemoptysis in this emergency case.
  • This intervention avoided the need for endotracheal intubation.

Implications:

  • Nebulized TXA presents a potentially valuable, rapidly accessible therapeutic option for emergency physicians managing massive hemoptysis.
  • It can serve as a primary treatment or a temporizing measure before definitive interventions.
  • Further research into nebulized TXA for hemoptysis is warranted.