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Updated: Feb 13, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[What is the goal blood pressure in non-diabetic chronic kidney disease?]
Thierry Krummel1, Nicolas Keller1, Éric Prinz1
1Service de néphrologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France.
Insights
Managing high blood pressure in chronic kidney disease (CKD) is crucial. This review analyzes recent trials to identify the optimal blood pressure target for slowing kidney disease progression and preventing cardiovascular events.
Area of Science:
- Nephrology
- Cardiology
- Clinical Trials
Background:
- Hypertension is common in renal disease, increasing cardiovascular and kidney disease risks.
- Optimal blood pressure management is vital for improving patient outcomes.
- Recent clinical trials have investigated specific blood pressure targets for non-diabetic chronic kidney disease.
Purpose of the Study:
- To review and analyze recent clinical trials on blood pressure targets in non-diabetic chronic kidney disease.
- To determine the most beneficial blood pressure target for renal disease progression and cardiovascular prevention.
Main Methods:
- Systematic review of recently published clinical trials.
- Analysis of studies focusing on blood pressure targets in patients with chronic non-diabetic kidney disease.
Main Results:
- Data from recent trials are being synthesized to evaluate different blood pressure targets.
- The analysis aims to identify a target that optimizes both renal and cardiovascular outcomes.
Conclusions:
- The optimal blood pressure target remains an active area of research.
- Evidence from recent trials will guide clinical practice for managing hypertension in CKD.
Abstract:
High blood pressure during renal disease is highly prevalent and an important risk factor for cardiovascular disease and renal progression. Its optimal management is therefore necessary to improve the prognosis of patients. Several trials concerning the blood pressure target in patients with chronic non-diabetic kidney disease have been published in recent years, we will detail them in this article in order to determine which blood pressure target provides the best benefit in terms of progression of renal diseases and cardiovascular prevention.
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