Related Experiment Video
Updated: Feb 13, 2026

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
Published on: June 20, 2020
Neurodevelopmental Status of Children aged 6-30 months with Severe Acute Malnutrition
Deepak Dwivedi1, Surendra Singh2, Jyoti Singh2
1Department of Pediatrics, SS Medical College, Rewa, Madhya Pradesh, India. Correspondence to: Dr Deepak Dwivedi, Assistant Professor (Pediatrics), D-2/8, Doctors Colony, Rewa 486 001, Madhya Pradesh, India. deepakdwi72@gmail.com.
Insights
Children with severe acute malnutrition (SAM) exhibit significant developmental delays, particularly in motor skills. Early intervention is crucial for improving neurodevelopmental outcomes in these vulnerable children.
Area of Science:
- Pediatrics
- Developmental Psychology
- Nutritional Science
Background:
- Severe acute malnutrition (SAM) is a critical global health issue affecting millions of children.
- Early childhood development is crucial for long-term health and well-being.
- Understanding the neurodevelopmental impact of SAM is essential for targeted interventions.
Purpose of the Study:
- To assess the developmental status of children aged 6-30 months diagnosed with severe acute malnutrition (SAM).
- To compare the neurodevelopmental outcomes of children with SAM against healthy controls.
Main Methods:
- A cross-sectional study design was employed.
- Participants included children with SAM from a therapeutic unit and healthy controls from a well-baby clinic.
- Neurodevelopment was evaluated using the Developmental Assessment Scale of Indian Infants (DASII), with a Developmental Quotient (DQ) ≤70 indicating delay.
Main Results:
- Children with SAM demonstrated significantly lower mean motor DQ (59.04) and mental DQ (62.1) compared to controls (P<0.0001).
- Developmental delays were more pronounced in skills typically acquired later in infancy.
- Motor DQ was more severely affected than mental DQ in the SAM group.
Conclusions:
- Children experiencing severe acute malnutrition exhibit significant neurodevelopmental delays.
- Motor development appears to be more adversely impacted by SAM than cognitive development.
- Findings underscore the need for early and comprehensive developmental support for children with SAM.
Objective:
This cross sectional study was done to assess the developmental status in children (6-30 mo old) with severe acute malutrition (SAM).
Methods:
Study subjects were enrolled from children in SAM therapeutic unit, and controls were selected from well-baby clinic of the institute. Neurodevelopment of both groups was assessed using the Developmental assessment scale of Indian infants (DASII). Developmental quotient (DQ) ≤70 was considered delayed.
Results:
Mean (SE) motor DQ 59.04 (0.74) and mental DQ 62.1 (0.57) was lower in SAM as compared to controls (both P<0.0001). Clusters of early age were normal but clusters with items of later infancy were delayed.
Conclusion:
Children with SAM show significant delay in development, and motor DQ is affected more than mental DQ.
Related Concept Videos
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Marcia's Theory of Identity Status
The Effect of Aging on Tissues
Drug Dosing: Infants and Children
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:

