Related Experiment Video
Updated: Feb 13, 2026
09:27
Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
Published on: January 5, 2016
18.1K
Parkinsonian syndromes: A review
Prachaya Srivanitchapoom1, Yuvadee Pitakpatapee1, Arpakorn Suengtaworn1
1Division of Neurology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Neurology India
|March 6, 2018
Summary
Parkinsonian syndromes encompass a growing list of diseases with Parkinson's-like symptoms. Accurate diagnosis relies on detailed examination and investigations to identify specific conditions and guide treatment.
Area of Science:
- Neurology
- Clinical Medicine
Background:
- Parkinsonian syndromes represent a spectrum of neurological disorders.
- The classification and understanding of these syndromes have evolved since James Parkinson's initial observations in 1817.
Purpose of the Study:
- To review the classification of parkinsonian syndromes.
- To comprehensively describe the characteristic features of common diseases within this spectrum.
Main Methods:
- Literature review focusing on parkinsonian syndromes.
- Analysis of epidemiological data, clinical features, diagnostic investigations, and treatment options.
Main Results:
- The spectrum of parkinsonian syndromes is expanding.
- Accurate diagnosis requires thorough clinical evaluation and appropriate investigations.
Conclusions:
- Effective management of parkinsonian syndromes necessitates precise diagnosis.
- This review provides an updated overview of epidemiology, clinical presentation, diagnostics, and therapeutics for commonly encountered parkinsonian syndromes.
Related Concept Videos
01:10Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
01:13Review and Preview
11.6K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
01:24Nephrotic Syndrome I : Introduction
697
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
697
01:30Acute Coronary Syndrome I: Introduction
1.1K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.1K
01:17Irritable Bowel Syndrome I: Introduction
1.1K
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.1K
01:27Restless Leg Syndrome and Night Terrors
584
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
584