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Related Concept Videos

Review and Preview01:10

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Acute Coronary Syndrome I: Introduction01:30

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
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Restless Leg Syndrome and Night Terrors01:27

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Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
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Related Experiment Video

Updated: Feb 13, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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Tremor syndromes: A review.

Nitish Kamble1, Pramod Kumar Pal1

  • 1Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

Neurology India
|March 6, 2018
PubMed
Summary

Tremor, a common involuntary movement disorder, involves various neural circuits. Understanding tremor phenomenology, neurological signs, and contributing factors is key for effective diagnosis and treatment.

Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Tremor is a frequent clinical manifestation of involuntary movement disorders.
  • Assessment requires evaluating tremor phenomenology, associated neurological signs, and potential medication or alcohol influences.

Purpose of the Study:

  • To review the pathophysiology and classification of tremors.
  • To discuss diagnostic approaches and therapeutic options for tremor.

Main Methods:

  • Review of existing literature on tremor generation and neurocircuitry.
  • Classification of tremors based on rest or action.
  • Discussion of neuroanatomical pathways implicated in different tremor types.

Main Results:

  • Essential tremor is linked to the olivocerebellar system.
Keywords:
Essential tremorHolmes tremorParkinson diseaseorthostatic tremorpalatal tremortremor

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  • Parkinson's disease tremor involves dopaminergic neuron loss and basal ganglia dysfunction.
  • Other tremors discussed include orthostatic, palatal, and Holmes tremor, each associated with specific circuit disruptions.
  • Conclusions:

    • Tremor generation involves complex interactions within the basal ganglia-cerebello-thalamic and dentate-olivary circuits.
    • Electrophysiological methods aid in tremor characterization.
    • Pharmacological and surgical interventions, including deep brain stimulation, can effectively manage tremor symptoms.