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Updated: Feb 13, 2026

Creation of Colonic Anastomosis in Mice
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Microvascular anastomosis with clips.

S Sood1, H Kim1

  • 1Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, U.S.A.

Neurology India
|March 6, 2018
PubMed
Summary
This summary is machine-generated.

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This study evaluated a modified Payr

Area of Science:

  • Vascular surgery
  • Surgical innovation
  • Experimental surgery

Background:

  • Vascular anastomosis is crucial for reconstructive surgery.
  • Suture techniques can be time-consuming and cause trauma.
  • Rapid, atraumatic methods are needed.

Purpose of the Study:

  • To evaluate a modified Payr's method for vascular anastomosis.
  • To assess its efficacy in high-flow jugulo-carotid anastomosis in rats.
  • To determine the technique's speed, ease of use, and patency.

Main Methods:

  • A modified Payr's method using a cylinder and external clip was employed.
  • End-to-end anastomosis was performed on rat jugular veins and carotid arteries.
  • Histopathology was conducted at one hour and chronically.

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Related Experiment Videos

Last Updated: Feb 13, 2026

Creation of Colonic Anastomosis in Mice
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Published on: January 17, 2019

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Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
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Main Results:

  • The technique was simple, rapid, and required short clamping time.
  • All grafts remained patent.
  • Early histopathology showed inflammation and endothelial disruption in veins, but intact arterial endothelium.
  • Chronic specimens demonstrated complete endothelization at the junction.

Conclusions:

  • The modified Payr's method offers a rapid, sutureless, and relatively atraumatic approach to vascular anastomosis.
  • It is suitable for high-flow vessels like the jugulo-carotid system.
  • Long-term patency and healing are promising, despite initial inflammatory responses.