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Updated: Feb 13, 2026

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation
Published on: March 8, 2018
Virtual Reality Rehabilitation With Functional Electrical Stimulation Improves Upper Extremity Function in Patients
Stephanie Hyeyoung Lee1, Ji-Yeong Lee1, Mi-Young Kim1
1Department of Rehabilitation Medicine, National Rehabilitation Center, Seoul, Republic of Korea.
Virtual reality combined with functional electrical stimulation (VR-FES) shows promise for improving upper extremity function in stroke survivors. VR-FES may be more effective than functional electrical stimulation (FES) alone for enhancing motor skills.
Area of Science:
- Neurorehabilitation
- Biomedical Engineering
Background:
- Chronic stroke often results in upper extremity hemiplegia, significantly impacting motor function and quality of life.
- Restoring upper extremity function is a critical goal in stroke rehabilitation.
Purpose of the Study:
- To compare the efficacy of virtual reality combined with functional electrical stimulation (VR-FES) against cyclic functional electrical stimulation (FES) for improving upper extremity function and health-related quality of life in chronic stroke patients.
Main Methods:
- A pilot, randomized, single-blind, controlled trial was conducted with 48 participants with chronic stroke and hemiplegia.
- The intervention group received VR-FES with virtual activity-based training, while the control group received cyclic FES only, with both groups completing 20 sessions over 4 weeks.
Main Results:
- VR-FES demonstrated a substantial increase in the Fugl-Meyer Assessment-distal score (P=.011) compared to FES alone.
- Marginal improvement was observed in the Jebsen-Taylor Hand Function Test-gross score (P=.057) with VR-FES.
- VR-FES generally showed greater improvements across other outcome measures, excluding the Stroke Impact Scale-activities of daily living/instrumental activities of daily living score.
Conclusions:
- Functional electrical stimulation (FES) combined with virtual reality (VR)-based rehabilitation may offer superior outcomes compared to cyclic FES for enhancing distal upper extremity gross motor performance poststroke.
- This pilot study suggests VR-FES as a potentially more effective rehabilitation strategy for stroke survivors.
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