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Updated: Feb 13, 2026
Methylated DNA Immunoprecipitation
Published on: January 2, 2009
MIRA: an R package for DNA methylation-based inference of regulatory activity
John T Lawson1,2, Eleni M Tomazou3, Christoph Bock4
1Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Summary:
DNA methylation contains information about the regulatory state of the cell. MIRA aggregates genome-scale DNA methylation data into a DNA methylation profile for a given region set with shared biological annotation. Using this profile, MIRA infers and scores the collective regulatory activity for the region set. MIRA facilitates regulatory analysis in situations where classical regulatory assays would be difficult and allows public sources of region sets to be leveraged for novel insight into the regulatory state of DNA methylation datasets.
Availability And Implementation:
http://bioconductor.org/packages/MIRA.
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