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Updated: Feb 13, 2026

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
Prospective Evaluation of a Low-Dose Radiation Fluoroscopy Protocol for Minimally Invasive Transforaminal Lumbar
Luis M Tumialán1,2, Justin C Clark1, Laura A Snyder1
1Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Background:
Recent research on radiation exposure in minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF) has led to the development of a low-dose radiation fluoroscopy protocol, with resulting reductions in fluoroscopy times and radiation exposures.
Objective:
To prospectively evaluate a previously reported low-dose radiation fluoroscopy protocol for MIS TLIF.
Methods:
A prospective evaluation of the low-dose radiation fluoroscopy protocol for MIS TLIF was performed for 65 consecutive patients. Total fluoroscopy time, radiation dose, and operative times were prospectively analyzed for all enrolled patients.
Results:
Sixty-five consecutive patients (43 women; 22 men) who underwent an MIS TLIF were prospectively enrolled in this study of the low-dose fluoroscopy protocol. A total of 260 pedicle screws were placed. The mean age of the patients was 63 years (range, 46-82 years). They had a mean operative time of 178.7 minutes (range, 119-247 minutes), a mean fluoroscopic time of 10.43 seconds (range, 5-24 seconds), and a mean radiation dose of 0.295 mGy × m2 (range, 0.092-0.314 mGy × m2).
Conclusion:
The combination of low-dose pulsed images and digital spot images in a low-dose protocol decreases fluoroscopy times and radiation doses in patients undergoing MIS TLIF without compromising visualization of the bony anatomy or the safety and efficiency of the procedure. The application of this low-dose protocol uncouples the otherwise linear relationship between fluoroscopy times and radiation dose. This is due primarily to the use of the digital spot technique. Equal emphasis should be placed on radiation dose and acquisition time to optimize this protocol.
Insights
A new low-dose radiation fluoroscopy protocol for minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF) significantly reduces radiation exposure and fluoroscopy time. This protocol maintains visualization and procedural safety, optimizing radiation dose and acquisition time.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Medical Imaging
Background:
- Radiation exposure is a concern in minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF).
- A low-dose radiation fluoroscopy protocol has been developed to reduce fluoroscopy times and radiation exposure.
- Previous research indicated the potential benefits of this protocol.
Purpose of the Study:
- To prospectively evaluate a previously reported low-dose radiation fluoroscopy protocol for MIS TLIF.
- To assess the impact of the protocol on fluoroscopy time, radiation dose, and operative efficiency.
Main Methods:
- Prospective evaluation of 65 consecutive patients undergoing MIS TLIF using a low-dose radiation fluoroscopy protocol.
- Analysis of total fluoroscopy time, radiation dose, and operative times for all enrolled patients.
- Placement of 260 pedicle screws was performed during the procedures.
Main Results:
- The study included 65 patients (43 women, 22 men) with a mean age of 63 years.
- Mean operative time was 178.7 minutes, mean fluoroscopic time was 10.43 seconds.
- Mean radiation dose was 0.295 mGy × m2, with a range of 0.092-0.314 mGy × m2.
Conclusions:
- The low-dose protocol, combining pulsed and digital spot images, reduces fluoroscopy time and radiation dose in MIS TLIF.
- Visualization of bony anatomy, procedure safety, and efficiency were not compromised.
- The protocol decouples fluoroscopy time from radiation dose, primarily due to digital spot imaging, emphasizing optimization of both dose and acquisition time.
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