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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

"Primary" dilated hearts

Aris Anastasakis1, Cristina Basso2

  • 1Inherited Cardiovascular Diseases Unit, 1st Department of Cardiology, University of Athens Medical School, 99, Michalakopoulou Ave, 11527 Athens, Greece.

International Journal of Cardiology
|March 7, 2018
PubMed

Insights

Dilated cardiomyopathy, a type of heart failure, presents unique characteristics. Future treatments and risk assessment for heart failure patients will likely depend on their specific pathological substrate.

Area of Science:

  • Cardiology
  • Pathology
  • Heart Failure Research

Background:

  • Dilated cardiomyopathy is a key component within the spectrum of heart failure.
  • Heart failure is recognized as a clinical syndrome defined by specific morphological and functional traits.

Purpose of the Study:

  • To highlight the importance of pathological substrate in dilated cardiomyopathy.
  • To suggest future directions for risk stratification and treatment in heart failure.

Main Methods:

  • Review of current understanding of dilated cardiomyopathy.
  • Analysis of the relationship between pathological substrate and clinical outcomes.

Main Results:

  • Dilated cardiomyopathy shares characteristics with the broader category of heart failure.
  • Progress in heart failure management has been made, but individualized approaches are needed.

Conclusions:

  • The specific pathological substrate is crucial for risk stratification in dilated cardiomyopathy.
  • Future therapeutic strategies for heart failure will likely be tailored to individual pathological findings.

Keywords:
Arrhythmogenic cardiomyopathy (ACM)Dilated cardiomyopathy (DCM)GeneticsHypo kinetic non dilated cardiomyopathy(HNDC)Risk stratification

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