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Updated: Feb 13, 2026

Isolation of Murine Intestinal Mesenchyme Resulting in a High Yield of Telocytes
Published on: March 24, 2023
CD117- and vimentin-positive telocytes in the bovine teat sphincter
M G Wagener1, S Leonhard-Marek2, J-D Häger1
1Institute for Anatomy, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Abstract:
Mastitis is a common economically relevant problem in dairy farming. As the major entry for pathogens is the papillary duct, one of the first defence mechanisms is the teat sphincter. This sphincter shows a rhythmic contractility of yet unknown origin. Searching for possible modulatory pacemaker cells, teat sphincters of eight cows were stained immunohistochemically with antibodies against CD117 and vimentin and evaluated microscopically for the presence of telocytes. CD117- and vimentin-positive telocytes with telopodes were found in close contact with smooth muscle cells. Our findings present a first evidence of telocytes in the teat of bovines.
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