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Updated: Feb 13, 2026

Postproduction Processing of Electrospun Fibres for Tissue Engineering
Published on: August 9, 2012
Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication
Indong Jun1, Hyung-Seop Han2,3, James R Edwards4
1Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford OX3 7LD, UK. indong.jun@ndorms.ox.ac.uk.
None:
Electrospinning has been used for the fabrication of extracellular matrix (ECM)-mimicking fibrous scaffolds for several decades. Electrospun fibrous scaffolds provide nanoscale/microscale fibrous structures with interconnecting pores, resembling natural ECM in tissues, and showing a high potential to facilitate the formation of artificial functional tissues. In this review, we summarize the fundamental principles of electrospinning processes for generating complex fibrous scaffold geometries that are similar in structural complexity to the ECM of living tissues. Moreover, several approaches for the formation of three-dimensional fibrous scaffolds arranged in hierarchical structures for tissue engineering are also presented.
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