Related Experiment Video
Updated: Feb 13, 2026
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Lower airway flow influences peak nasal inspiratory flow in school-aged children
H Pite1, L Pimenta1, A C Henriques1
1Allergy Center, CUF Descobertas Hospital and CUF Infante Santo Hospital, Lisbon, Portugal.
Insights
Peak nasal inspiratory flow (PNIF) in children correlates with lung function (FEV1 and PEF), not subjective asthma control. PEF, age, and gender best predict PNIF, aiding its interpretation in rhinitis and asthma.
Area of Science:
- Pediatric Respiratory Medicine
- Allergy and Immunology
Background:
- Rhinitis and asthma commonly co-occur in children.
- Peak nasal inspiratory flow (PNIF) measures nasal obstruction.
- The relationship between lower airway function and PNIF in children is understudied.
Purpose of the Study:
- To investigate associations between PNIF and lung function (FEV1, PEF) in children with allergic rhinitis and asthma.
- To explore the link between PNIF and subjective control assessments (CARATkids).
Main Methods:
- Sixty-five children (6-12 years) with allergic rhinitis and asthma and 24 healthy controls underwent PNIF and spirometry.
- Nasal decongestion and bronchodilation tests were performed.
- Multiple linear regression analyzed associations, using CARATkids for control assessment.
Main Results:
- PNIF correlated with FEV1 and PEF, irrespective of rhinitis/asthma diagnosis.
- Peak expiratory flow (PEF), age, and gender were the strongest predictors of PNIF.
- No significant association was found between PNIF and CARATkids scores, except for self-reported nasal obstruction.
Conclusions:
- PEF, age, and gender are crucial for interpreting PNIF in school-aged children.
- PNIF can supplement subjective assessments for managing allergic rhinitis and asthma control.
Background:
Rhinitis and asthma frequently coexist. Peak nasal inspiratory flow (PNIF) objectively evaluates nasal obstruction. Lower airway flow's impact on PNIF has seldom been analysed in children. We aimed to study the associations between PNIF and: 1)forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF) in children with allergic rhinitis and asthma and healthy controls; 2)allergic rhinitis and asthma control subjective evaluation.
Methods:
Sequential assessments of PNIF before and after nasal decongestion and spirometry with bronchodilation test were performed in 65 children (6-12 years) with allergic rhinitis and asthma, and 24 gender, age-matched healthy controls. The Control of Allergic Rhinitis and Asthma Test in children (CARATkids) was used for control assessment. Associations were investigated by multiple linear regression models.
Results:
Baseline and decongested PNIF correlated with baseline and post-bronchodilation FEV1 and PEF, observed independently of rhinitis and asthma diagnosis. The best model for PNIF included PEF, age and gender. No association was found between PNIF and CARATkids scores, except for nasal obstruction self-report.
Conclusion:
In school-aged children, besides age and gender, PEF values should ideally be known to interpret PNIF values. PNIF can be complementary to subjective control assessment in children with allergic rhinitis and asthma.
More Related Videos
08:05Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
Published on: June 30, 2020
12:08Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells
Published on: March 10, 2016
Related Concept Videos
02:39Gene Flow
01:23Flow Cytometry
In...
01:17Flow Sheet
Here's a closer look at the examples of flowsheets commonly used by nurses:
Graphic Sheet Documentation:
01:12Flow Table Test
Concrete is placed within a truncated cone mold that is 8 inches high with an 8-inch base diameter and a 5-inch top diameter. The...
01:28Irrotational Flow
01:24Turbulent Flow