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Procalcitonin Testing to Guide Antibiotic Therapy in Acute Upper and Lower Respiratory Tract Infections
Philipp Schuetz1,2, Yannick Wirz1, Beat Mueller1,2
1Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland.
Clinical Question:
Is the use of procalcitonin for guiding antibiotic decisions in patients with acute upper and lower respiratory tract infections associated with improved clinical outcomes compared with usual care?
Bottom Line:
Among patients with varying types and severity of acute respiratory infection, using procalcitonin to guide decisions about antibiotics is associated with lower rates of antibiotic exposure, antibiotic-related adverse effects, and mortality.
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