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Updated: Feb 13, 2026

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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
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[Pregnancy in women with solid-organ transplants]
Ceska Gynekologie
|March 8, 2018
Summary
Pregnancies after solid organ transplantation carry higher risks for mothers and newborns, including preeclampsia and premature birth. Careful planning and specialized care can lead to healthy outcomes for women who have undergone transplantation.
Area of Science:
- Obstetrics and Gynecology
- Transplant Medicine
- Reproductive Health
Background:
- Solid organ transplantation is a life-saving procedure, but subsequent pregnancies require careful management.
- Women of childbearing potential undergoing transplantation face unique risks during pregnancy.
Purpose of the Study:
- To evaluate maternal and fetal risks associated with pregnancies and deliveries in women post-solid organ transplantation.
- To review current practices and outcomes for pregnant transplant recipients.
Main Methods:
- Systematic literature search of major databases (Web of Science, PubMed, etc.) from 1958-2017.
- Analysis of review articles focusing on solid organ transplantation and pregnancy outcomes.
Main Results:
- Pregnancy post-transplant is linked to increased risks of preeclampsia, comorbidities, premature delivery, and low birth weight infants.
- Lung transplant recipients face the highest complication rates.
- Common immunosuppressants include calcineurin inhibitors, azathioprine, and prednisone.
Conclusions:
- Pregnancy after solid organ transplantation is high-risk but manageable.
- Successful outcomes depend on early transplantation, patient compensation, planned pregnancy, appropriate immunosuppression, and specialized prenatal/obstetric care.
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