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Experience with long-term peritoneal insulin infusion from external pumps.
Summary
Continuous peritoneal insulin infusion (CPII) is a feasible long-term treatment for diabetes, maintaining satisfactory blood glucose control. While minor issues occurred, most patients found the therapy acceptable, with few dropouts.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Medical Devices
Background:
- Diabetes mellitus requires effective long-term insulin management.
- Continuous peritoneal insulin infusion (CPII) offers a potential alternative delivery method.
Purpose of the Study:
- To evaluate the long-term acceptability and feasibility of CPII using external pumps.
- To assess blood glucose control and identify complications associated with CPII.
Main Methods:
- A cohort of 40 insulin-dependent diabetic patients received CPII for 1-27 months.
- Data collection included blood glucose levels, complication monitoring, and patient feedback.
Main Results:
- Satisfactory blood glucose control was maintained, with glycosylated haemoglobin levels averaging 8.1%.
- Major complications included peritonitis and episodes of hypoglycemia/hyperglycemia; minor issues were frequent and pump/catheter-related.
- One-year pump and catheter survival rates were 46% and 70%, respectively.
Conclusions:
- CPII is a feasible and acceptable long-term treatment option for selected diabetic patients.
- Effective management relies on patient selection, education, and medical support.
- Intraperitoneal insulin delivery may offer physiological advantages.