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Related Experiment Video

Updated: Feb 13, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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A continuous-flow external ventricular assist device for cardiogenic shock: Evolution over 10 years.

Masahiko Ando1, Arthur R Garan2, Hiroo Takayama1

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Columbia University Medical Center, New York, NY.

The Journal of Thoracic and Cardiovascular Surgery
|March 8, 2018
PubMed
Summary

Continuous-flow external ventricular assist devices (VADs) show improved outcomes for cardiogenic shock patients. Recent advancements in VAD use and configurations led to better survival rates in refractory cardiogenic shock.

Keywords:
bridgecardiogenic shockextracorporeal membrane oxygenationoutcomeventricular assist device

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Area of Science:

  • Cardiology
  • Medical Devices
  • Critical Care Medicine

Background:

  • Percutaneous mechanical circulatory support (MCS) use for cardiogenic shock is rising.
  • Existing MCS devices have limitations in flow, unloading, durability, and mobility.
  • Continuous-flow external ventricular assist devices (VADs) are increasingly used for cardiogenic shock.

Purpose of the Study:

  • To evaluate the role of temporary VADs in contemporary cardiogenic shock treatment.
  • To analyze changes in indications, device configurations, and outcomes over time.
  • To compare early and late outcomes of VAD use in two distinct eras.

Main Methods:

  • Retrospective review of 252 patients undergoing continuous-flow external VAD insertion (2007-2016).
  • Cohort divided into two eras: 2007-2011 (Era 1) and 2012-2016 (Era 2).
  • Comparison of indications, device configurations, and patient outcomes between the two eras.

Main Results:

  • Significant changes in indications and device configurations observed between eras.
  • Era 2 showed increased use of preoperative percutaneous MCS and minimally invasive VAD configurations.
  • In-hospital mortality and 1-year survival were significantly improved in Era 2 compared to Era 1.

Conclusions:

  • Improved outcomes in the recent era may be linked to evolving practice patterns with continuous-flow external VADs.
  • Continuous-flow external VADs represent a valuable option for refractory cardiogenic shock.
  • Further research into optimal VAD strategies is warranted.