Related Experiment Video

Updated: Feb 13, 2026

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
10:01

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice

Published on: October 17, 2018

8.5K

Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential

Gary Wong1,2,3,4, Xiang-Guo Qiu3,4

  • 1Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Shenzhen Guangzhou 518020, China. garyckwong@hotmail.com.

Zoological Research
|March 8, 2018
PubMed

Keywords:
Animal modelArenavirusBunyavirusFilovirusFlavivirusHenipavirusIfnarMiceTogavirus

More Related Videos

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses10:10

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses

Published on: November 16, 2016

14.3K
Influenza A Virus Studies in a Mouse Model of Infection10:44

Influenza A Virus Studies in a Mouse Model of Infection

Published on: September 7, 2017

29.9K

Related Concept Videos

Types of Receptors: Internal Receptors01:07

Types of Receptors: Internal Receptors

Many cellular signals are hydrophilic and cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind intracellular receptors that reside within the cell cytoplasm or nucleus. Many mammalian steroid hormones and nitric oxide (NO) gas use this cell signaling mechanism.
Similar to membrane-bound receptors, the binding of a ligand to the intracellular receptor of causes a conformational change in the...
32.7K
Types of Receptors: Cell Surface Receptors01:28

Types of Receptors: Cell Surface Receptors

Cell-surface receptors, also known as transmembrane receptors, are cell surface, membrane-anchored (integral) proteins that bind to external ligand molecules. This type of receptor spans the plasma membrane and performs signal transduction, converting an extracellular signal into an intracellular signal. Ligands that interact with cell-surface receptors do not have to enter the cell that they affect. Cell-surface receptors are also called cell-specific proteins or markers because they are...
27.7K
Types of Potential Energy01:16

Types of Potential Energy

Potential energy is also known as energy at rest or stored energy. Common types of potential energy include the gravitational potential energy stored in an apple hanging from a tree, the electrical potential energy stored in an object due to the attraction or repulsion of electric charges, and the chemical potential energy stored in the bonds between atoms and molecules. Additionally, the nuclear energy stored in an atomic nucleus and the elastic energy stored in a stretched spring due to its...
10.2K
What are Viruses?00:50

What are Viruses?

Overview
128.4K
The Two-State Receptor Model01:29

The Two-State Receptor Model

The two-state receptor model explains a drug's interaction with receptors, such as G protein-coupled receptors and ligand-gated ion channels, to induce or inhibit a biological response. When no natural ligands are present, a receptor exists in an equilibrium of inactive (Ri) and active (Ra) conformations. The inactive form does not produce a response, while the active form generates a basal effect known as constitutive activity.
The binding affinity of a drug determines its interaction with...
3.1K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
599