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Routine Angiographic Follow-Up After Coronary Artery Disease Revascularization: Is Seeing Believing?
Harsh Agrawal1,2, Mohamed Teleb3, Saba Lahsaei4
1Division of Interventional Cardiology, Department of Internal Medicine, St. Elizabeth's Medical Center, Tufts School of Medicine, Boston, MA, USA. harshagrawal@hotmail.com.
Insights
Routine coronary angiography after percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is not recommended for asymptomatic patients. Current evidence does not support its use, despite theoretical benefits for early intervention.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Clinical Outcomes Research
Background:
- Coronary artery disease (CAD) is a leading cause of global mortality and morbidity.
- Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are common revascularization procedures.
- Restenosis and stent thrombosis remain significant complications of PCI.
Purpose of the Study:
- To review the existing literature on the outcomes of routine angiography after PCI or CABG.
- To evaluate the potential benefits and drawbacks of routine post-revascularization angiography.
Main Methods:
- Systematic review of published literature.
- Analysis of data from randomized clinical trials and observational studies.
- Evaluation of current guidelines and expert recommendations.
Main Results:
- Recent data from clinical trials do not support routine coronary angiography in asymptomatic patients post-revascularization.
- Some exploratory studies suggest a potential role in left main or complex coronary interventions, but these findings lack robust evidence.
- The overall incidence of coronary heart disease (CHD) in the USA is high, with millions affected annually.
Conclusions:
- Current evidence does not support the routine use of coronary angiography for asymptomatic patients following PCI or CABG.
- Further randomized controlled trials are needed to definitively establish the role, if any, of routine angiography in specific patient subsets.
Purpose Of The Review:
Coronary artery disease is a major cause of mortality and morbidity in the world, and PCI and CABG account for over a million procedures performed annually in the USA. The goal of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is to achieve complete revascularization (CR) if at all possible. However, restenosis and stent thrombosis (ST) remain the Achilles heel of contemporary PCI with restenosis rates between 10 and 30% with bare metal stents to 5-15% after drug-eluting stents and ST rates of around 0.8 vs 1.2%, respectively. Routine angiography after revascularization seems theoretically attractive as this may allow intervention before clinical events occur. In this manuscript, we review the literature regarding routine angiography after PCI or CABG and its outcomes.
Recent Findings:
According to the 2016 update from the American Heart Association (AHA), 15.5 million people above the age of 20 have coronary heart disease (CHD) in the USA. The prevalence of CHD is now almost similar in both men and women, and one American suffers from a myocardial infarction (MI) every 42 s. Recent data from randomized clinical trials and observational studies does not support the use of routine coronary angiography after revascularization in asymptomatic patients. There are some studies which show that routine angiography may have a role in left main or complex coronary interventions; however, these findings are exploratory and were not seen in randomized trials. After reviewing the data on routine angiography after coronary revascularization, we came to the conclusion that current data does not support the use of routine angiography for asymptomatic patients. However, there is a lack of randomized controlled trial in this field with only one recent trial reporting negative outcomes.
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