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Updated: Feb 13, 2026

Murine Renal Transplantation Procedure
Published on: July 10, 2009
Role of crossmatch testing when Luminex-SAB is negative in renal transplantation
Kumar Jayant1, Isabella Reccia1, Bridson M Julie2
1Department of Surgery and Cancer; Faculty of Medicine, Hammersmith Hospital, Imperial College London, UK.
Abstract:
The human leukocyte antigen (HLA) system plays an important role in the acceptance of renal graft. Long and better graft survival has been reported in patients with HLA-identical siblings and a nonreactive cytotoxicity assay (CDC). New methods of HLA-typing and anti-HLA antibody detection techniques such as flow cytometry, solid-phase immunoassays, or antigen bead assays have further improved the outcomes of renal transplant recipients. In the present review, the explicit details of these methodologies are discussed in detail.
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