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Photodeposition of Pd onto Colloidal Au Nanorods by Surface Plasmon Excitation
Published on: August 15, 2019
High sensitive detection of copper II ions using D-penicillamine-coated gold nanorods based on localized surface
Yoochan Hong1, Seongjae Jo2, Joohyung Park2
1Department of Medical Device, Daegu Research Center for Medical Devices and Green Energy, Korea Institute of Machinery & Materials (KIMM), Daegu 42994, Republic of Korea.
Abstract:
In this paper, we describe the development of a nanoplasmonic biosensor based on the localized surface plasmon resonance (LSPR) effect that enables a sensitive and selective recognition of copper II ions. First, we fabricated the nanoplasmonics as LSPR substrates using gold nanorods (GNR) and the nano-adsorption method. The LSPR sensitivity of the nanoplasmonics was evaluated using various solvents with different refractive indexes. Subsequently, D-penicillamine (DPA)-a chelating agent of copper II ions-was conjugated to the surface of the GNR. The limit of detection (LOD) for the DPA-conjugated nanoplasmonics was 100 pM. Furthermore, selectivity tests were conducted using various divalent cations, and sensitivity tests were conducted on the nanoplasmonics under blood-like environments. Finally, the developed nanoplasmonic biosensor based on GNR shows great potential for the effective recognition of copper II ions, even in human blood conditions.
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