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Updated: Feb 13, 2026

Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain
Published on: June 1, 2015
Sequestrated lateral ventricle due to tuberculosis
P K Gupta1, A Anjaneyulu1, R Borgohain1
1Department of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad - 500 492, India.
A rare case of isolated tubercular obstruction of the foramen of Monro caused recurrent hydrocephalus in a young man. Surgical and medical treatments were initially effective but symptoms returned, necessitating further investigation.
Area of Science:
- Neurology
- Neurosurgery
- Infectious Diseases
Background:
- Raised intracranial pressure and neurological deficits are critical symptoms.
- Unilateral ventricular dilatation suggests an obstructive process.
- Tubercular pathology can manifest in the central nervous system.
Purpose of the Study:
- To report a rare case of isolated tubercular obstruction of the foramen of Monro.
- To discuss the pathogenesis and management of this unusual condition.
- To highlight the diagnostic challenges and treatment strategies.
Main Methods:
- Clinical presentation and neurological examination.
- Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) of the brain.
- Ventriculography and Cerebrospinal Fluid (CSF) analysis.
Main Results:
- Initial CT revealed right lateral ventricle dilatation and ventriculography showed blockage of the right foramen of Monro.
- Despite shunt surgery and antitubercular drugs, symptoms recurred.
- Recurrence was linked to a sequestrated left lateral ventricle, with CSF findings suggestive of tuberculosis.
Conclusions:
- Isolated tubercular obstruction of the foramen of Monro is an exceptionally rare cause of hydrocephalus.
- Recurrence of symptoms may indicate incomplete treatment or a distinct pathological process.
- Management requires a comprehensive approach, considering both surgical and medical interventions tailored to the specific presentation.
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