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Updated: Feb 13, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Leveraging user perspectives for insight into cannabis concentrates
Patricia A Cavazos-Rehg1, Melissa J Krauss1, Shaina J Sowles1
1a Department of Psychiatry , Washington University School of Medicine , St. Louis , MO , USA.
Highly concentrated cannabis use is rising, with many young adults reporting frequent use and experiencing side effects like confusion and paranoia. More research and policies are needed to ensure safe cannabis concentrates consumption.
Area of Science:
- Cannabis Research
- Public Health
- Substance Use Studies
Background:
- Increasing popularity of highly concentrated cannabis products in the US.
- Limited understanding of the potential risks associated with cannabis concentrates use.
- Need for research into the health implications of novel cannabis forms.
Purpose of the Study:
- Investigate patterns of cannabis concentrates consumption among young adults.
- Understand the perceived outcomes and side effects of using cannabis concentrates.
- Gather user perspectives on the experiences with cannabis concentrates.
Main Methods:
- Survey of 234 adults aged 18-35 who have used cannabis concentrates in the past 6 months.
- Data collection on frequency, motivations (medical/recreational), and experienced effects (physiological/psychological).
- Analysis of co-use patterns with other substances and cannabis forms.
Main Results:
- 27.8% of participants reported frequent cannabis concentrates use (≥10 days/month).
- Frequent use was associated with medical purposes and legal state residency.
- Reported side effects included altered reality/confusion (23.3%), rapid heartbeat (11.2%), lung pain (9.9%), and paranoia (6.9%).
- High rates of co-use observed: 72.6% with other cannabis forms, 57.7% with alcohol, 22.6% with other drugs.
Conclusions:
- Further research on cannabis concentrates use in the US is essential.
- Development of research-informed policies is crucial for promoting safe and responsible use.
- Protecting frequent users from potential negative side effects requires targeted interventions and policies.
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