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Updated: Feb 13, 2026

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
Published on: December 13, 2016
Synthesis of Cyclohexanones through a Catalytic Cationic Cyclization of Alkynols or Enynes
Pedro Alonso1, Raquel Fontaneda1, Pilar Pardo1
1Instituto Universitario de Química Organometálica "Enrique Moles" , Universidad de Oviedo , Julián Clavería 8 , E-33006 Oviedo , Spain.
Abstract:
A novel procedure for the synthesis of cyclohexanones from alkynol or enyne derivatives through a cationic cyclization has been developed. The key points to obtain the six-membered ring derivatives are the use of starting materials containing a terminal alkyne, the use of tetrafluoroboric acid as a promoter of the cationic cyclization, and the appropriate selection of 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) as solvent. This strategy can be extended to the biomimetic cationic cyclization of several terpene-derived polyenynes.
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