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Updated: Jan 1, 2026

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
Published on: August 17, 2022
PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix
Giovanna Ambrosini1,2, Romain Groux1,2, Philipp Bucher1,2
1The Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL).
Summary:
Transcription factors regulate gene expression by binding to specific short DNA sequences of 5-20 bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-resident genomes for matches to a user-supplied PWM or transcription factor binding site model from a public database.
Availability And Implementation:
The web server and source code are available at http://ccg.vital-it.ch/pwmscan and https://sourceforge.net/projects/pwmscan, respectively.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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