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Published on: January 21, 2010
Publisher Correction: Medial preoptic circuit induces hunting-like actions to target objects and prey
Sae-Geun Park1, Yong-Cheol Jeong1, Dae-Gun Kim1,2
1Department of Biological Sciences, KAIST, Daejeon, Korea.
Abstract:
In the version of this article initially published, a sentence in the fifth paragraph of the Results read, "Immunohistochemistry revealed that VGLUT2+ MPA neurons rarely expressed CaMKIIα, which is a putative marker for subcortical glutamatergic neurons." It should have read, "Immunohistochemistry revealed that CaMKIIα+ MPA neurons rarely expressed VGLUT2, which is a putative marker for subcortical glutamatergic neurons." The error has been corrected in the HTML and PDF versions of the article. In the supplementary information originally posted online, the wrong version of Supplementary Fig. 1 was posted and some of the supplementary videos were interchanged. In the corrected Supplementary Fig. 1, the top right subpanel was added and the original Supplementary Fig. 1a was divided into 1a and 1b, with subsequent panels incremented accordingly. The legend was changed from "a. Schematic illustrating electrical lesioning of the rat anterior hypothalamus. Electrical lesion areas (gray) in five representative brain sections are depicted. Scale bar, 1 mm" to "a. Repetitive electrical stimulations of the anterior hypothalamus using bipolar electrodes (Left) caused a lesion at the hypothalamic area (middle, marked by asterisk) successfully in 7 rats (Right, overlapped images of brain sections located from the bregma -0.24 mm). Scale bar, 1 mm. b. Electrical lesion areas (gray) in five representative brain sections from anterior to posterior are depicted." The errors have been corrected online.
Insights
This study corrects errors in a previous publication regarding neuronal markers and supplementary figures. The updated findings clarify the expression of CaMKIIα and VGLUT2 in MPA neurons and provide accurate supplementary data.
Area of Science:
- Neuroscience
- Molecular Biology
Context:
- Investigating neuronal populations in the medial preoptic area (MPA).
- Utilizing immunohistochemistry to identify specific neuronal markers.
Purpose:
- To correct erroneous statements regarding the co-expression of VGLUT2 and CaMKIIα in MPA neurons.
- To rectify inaccuracies in supplementary figures and videos, ensuring data integrity.
Summary:
- The study corrects a misstatement identifying CaMKIIα as a marker for subcortical glutamatergic neurons, clarifying that CaMKIIα+ MPA neurons rarely express VGLUT2.
- Updated supplementary materials provide accurate schematics and images of anterior hypothalamus electrical lesioning and associated data.
Impact:
- Ensures accurate representation of neuronal marker expression in the medial preoptic area.
- Improves the reliability and reproducibility of research findings by correcting supplementary data and figures.
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