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The Lateral Prefrontal Cortex and Selection/Inhibition in ADHD
1Hebrew University of Jerusalem, Jerusalem, Israel.
Frontiers in Human Neuroscience
|March 9, 2018
Summary
This study reveals the lateral prefrontal cortex manages selection and inhibition in mental processing. It links specific lateral prefrontal cortex areas to challenges in attention-deficit/hyperactivity disorder (ADHD).
Area of Science:
- Neuroscience
- Cognitive Psychology
Background:
- Previous research implicated the medial prefrontal cortex in integrating information into mental representations.
- This medial prefrontal cortex function was linked to challenges in Autism Spectrum Disorders.
Purpose of the Study:
- To investigate the role of the lateral prefrontal cortex in cognitive processing.
- To classify attention-deficit/hyperactivity disorder (ADHD) challenges based on lateral prefrontal cortex functions.
Main Methods:
- Analysis of subareas within the lateral prefrontal cortex.
- Correlating specific lateral prefrontal cortex functions with ADHD-related difficulties.
Main Results:
- Evidence suggests the lateral prefrontal cortex is crucial for selecting and inhibiting perceptual, memory, emotional, and motor aspects of processing.
- Specific difficulties in selection/inhibition were linked to distinct subareas of the lateral prefrontal cortex.
Conclusions:
- The lateral prefrontal cortex plays a key role in cognitive control through selection and inhibition.
- This framework helps classify and understand the neurobiological underpinnings of ADHD symptoms.
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