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Related Concept Videos

Nursing Clinical Information System01:27

Nursing Clinical Information System

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Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
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Clinical Trials01:16

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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

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Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Related Experiment Video

Updated: Feb 13, 2026

A Melanoma Patient-Derived Xenograft Model
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[Soft tissue melanoma: a clinical case].

Rachid Frikh1, Siham Oumakhir1, Hafsa Chahdi2

  • 1Service de Dermatologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc.

The Pan African Medical Journal
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Summary

Soft tissue melanoma, a rare cancer, was initially termed clear cell sarcoma. This report details a young man

Keywords:
Soft tissue melanomaextremitiespedicled tumor

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Area of Science:

  • Oncology
  • Dermatopathology

Background:

  • Soft tissue melanoma, initially described as clear cell sarcoma in 1965, was renamed in 1983.
  • This rare malignancy shares immunohistochemical similarities with cutaneous melanoma.

Observation:

  • A 22-year-old male presented with a molluscoid lesion on his ankle.
  • The lesion showed no overt clinical signs of malignancy.

Findings:

  • Histological examination confirmed the diagnosis of soft tissue melanoma.
  • The case highlights a rare presentation of this soft tissue sarcoma.

Implications:

  • Emphasizes the importance of histological confirmation for diagnosing rare soft tissue tumors.
  • Contributes to understanding the clinical and pathological spectrum of soft tissue melanoma.