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Updated: Feb 13, 2026

Author Spotlight: Innovative Use of nsPEF to Boost Peripheral Nerve Regeneration
Published on: May 3, 2024
Polymeric scaffolds for three-dimensional culture of nerve cells: a model of peripheral nerve regeneration
Radamés Ayala-Caminero1, Luis Pinzón-Herrera2, Carol A Rivera Martinez1
1Bioengineering Program, University of Puerto Rico Mayaguez, Call Box 9000, Mayagüez, Puerto Rico, 00681-9000, USA.
Abstract:
Understanding peripheral nerve repair requires the evaluation of 3D structures that serve as platforms for 3D cell culture. Multiple platforms for 3D cell culture have been developed, mimicking peripheral nerve growth and function, in order to study tissue repair or diseases. To recreate an appropriate 3D environment for peripheral nerve cells, key factors are to be considered including: selection of cells, polymeric biomaterials to be used, and fabrication techniques to shape and form the 3D scaffolds for cellular culture. This review focuses on polymeric 3D platforms used for the development of 3D peripheral nerve cell cultures.
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