Elucidation of non-intentionally added substances migrating from polyester-polyurethane lacquers using automated
Elsa Omer1,2,3, Ronan Cariou4, Gérald Remaud2
1LABERCA, Oniris, INRA, Université Bretagne-Loire, Route de Gachet, 44307, Nantes, France.
Analytical and Bioanalytical Chemistry
|March 9, 2018
Summary
A new untargeted strategy successfully identified non-intentionally added substances (NIAS) in polyester-polyurethane lacquers. This method elucidated over 80% of migrating substances, including cyclic polyester oligomers, enhancing food contact material safety.
Area of Science:
- Analytical Chemistry
- Polymer Science
- Food Safety
Background:
- Non-intentionally added substances (NIAS) can migrate from food contact materials.
- Polyester-polyurethane lacquers are used in food packaging, necessitating NIAS identification.
Purpose of the Study:
- To develop and apply an untargeted strategy for identifying NIAS in lacquers.
- To elucidate the chemical identity of migrating substances from polyester-polyurethane coatings.
Main Methods:
- Liquid chromatography-high resolution mass spectrometry (LC-HRMS) in full scan mode.
- Data processing using R-environment (xcms, CAMERA) and a homemade database.
- Analysis of predicted and unpredicted migrating oligomers and monomers.
Main Results:
- Identified 14 and 17 cyclic predicted polyester oligomers in two lacquers.
- Tentatively elucidated four monomers responsible for several oligomer series.
- Assigned hypotheses to up to 90% of cumulated intensities for migrating substances.
Conclusions:
- The developed untargeted strategy is effective for NIAS identification in coatings.
- The approach significantly enhances the understanding of migrating substances from food contact materials.
- This method contributes to improved safety assessments of food packaging.
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