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Updated: Feb 13, 2026
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
Keratoconus-like tomographic changes in a case of recurrent interstitial keratitis
Marie-Sophie Hanet1, Annette Zimpfer2, Sabine Lepper3
1Department of Ophthalmology, Saarland University Medical Center, 66424, Homburg, Saar, Germany. msophiehanet@hotmail.com.
Background:
The purpose of this report was to describe a single case of recurrent interstitial keratitis in a young patient leading to keratoconus-like corneal changes.
Results:
Over the 2 years follow-up, the patient developed clinical signs of keratoconus with Vogt's striae, Fleischer Ring and paracentral stromal thinning in the affected eye only. The tomographic measurements revealed a rapid reduction of corneal thickness from 581 to 303 μm and an irregular steepening of the pathological cornea. True net corneal power increased from 42.8 to 48.8 dioptres (D) and maximal power of the anterior surface from 44.9 to 66.9 D. Best-corrected visual acuity (BCVA) decreased from 20/20 to 20/200. A penetrating excimer laser keratoplasty was performed to restore vision and corneal stability.
Conclusion:
Keratoconus-like changes can occur in young patients with recurrent interstitial keratitis and request corneal transplantation.
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