An agenda for 21st century neurodevelopmental medicine: lessons from autism

A Klin1, W Jones1

  • 1Children's Healthcare of Atlanta and Emory University School of Medicine. Atlanta, Georgia, EE.UU.

Revista De Neurologia
|March 9, 2018
PubMed

Insights

Child neurology can lead public health initiatives to optimize neurodevelopmental outcomes. Advancements in neuroscience and technology enable early diagnosis and effective treatments for children facing developmental challenges.

Area of Science:

  • Neurodevelopmental Medicine
  • Public Health
  • Developmental Social Neuroscience

Background:

  • Children face diverse genetic, prenatal, and environmental risks impacting early brain development and leading to lifelong disabilities.
  • Neurodevelopmental disorders like autism are increasingly understood through advancements in developmental social neuroscience.
  • Implementation science provides frameworks for integrating new interventions into healthcare systems.

Purpose of the Study:

  • To outline a future vision for neurodevelopmental medicine integrated with public health efforts.
  • To explore how advancements can optimize neurodevelopmental outcomes in at-risk children.
  • To highlight the potential of new technologies for diagnosis and treatment delivery.

Main Methods:

  • Leveraging advances in developmental social neuroscience and implementation science.
  • Capitalizing on early neuroplasticity and quantifying social-communicative development trajectories.
  • Developing high-throughput, cost-effective diagnostic technologies and community-viable treatments.

Main Results:

  • Emerging technologies facilitate early, accessible diagnosis and treatment for neurodevelopmental disorders.
  • Integrated healthcare delivery systems can seamlessly incorporate these new solutions.
  • Potential exists to extend these approaches to other at-risk populations, including premature infants and those with congenital heart disease.

Conclusions:

  • A public health approach focusing on optimal early brain development is essential.
  • This mirrors successful public health campaigns for prenatal care, nutrition, and vaccination.
  • Child neurology is poised to lead this paradigm shift in optimizing child neurodevelopment.

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